Last update
5/4/2026
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Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
USERS' SCORE
Good
Based on 8 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Magnesium (elemental) (from Magnesium Oxide, Magnesium Citrate and Magnesium Aspartate)
400 mg
95%
Top Medical Research Studies
8
Magnesium enhances ibutilide for TAF
We explored how magnesium sulfate influences ibutilide's effectiveness in converting atrial flutter. This randomized, placebo-controlled study included 117 patients with typical (TAF) or atypical atrial flutter (AAF).
Results showed that magnesium significantly enhanced conversion rates in TAF patients—85% with magnesium compared to 59% with placebo. However, for AAF patients, the difference was not significant, with conversion rates at 48% versus 56%. Importantly, magnesium did not impact QT interval durations.
Results showed that magnesium significantly enhanced conversion rates in TAF patients—85% with magnesium compared to 59% with placebo. However, for AAF patients, the difference was not significant, with conversion rates at 48% versus 56%. Importantly, magnesium did not impact QT interval durations.
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5
We investigated the effects of magnesium sulphate on patients recovering from coronary artery bypass grafting. Over four days, patients received either magnesium or a placebo.
Our findings indicated that while magnesium reduced the duration of atrial flutter, it did not decrease the number of patients experiencing these arrhythmias. Additionally, patients on magnesium had fewer abnormal heartbeats. Despite promising results, magnesium treatment did not significantly alter the electrolyte levels we monitored.
Overall, magnesium appears beneficial in managing the severity of postoperative arrhythmias.
Our findings indicated that while magnesium reduced the duration of atrial flutter, it did not decrease the number of patients experiencing these arrhythmias. Additionally, patients on magnesium had fewer abnormal heartbeats. Despite promising results, magnesium treatment did not significantly alter the electrolyte levels we monitored.
Overall, magnesium appears beneficial in managing the severity of postoperative arrhythmias.
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8
Magnesium enhances ibutilide's effectiveness
We explored the combination of magnesium and ibutilide to help convert persistent atrial flutter or fibrillation in patients with rheumatic heart disease. In this study with 33 patients, raising magnesium levels significantly improved the rate of conversion to normal sinus rhythm. Astonishingly, 76% of patients successfully transitioned to sinus rhythm post-treatment. The analysis indicated that higher magnesium levels, particularly above 3.8 mg/dl, were linked to increased success rates. This suggests that magnesium could enhance ibutilide’s effectiveness in treating these heart rhythm issues.
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Most Useful Reviews
7.5
Promotes calmness
41 people found this helpful
Calmness, balance, sleep - that's what I experience. I can't speak for others, but it aids me in managing overwork, calming my nerves. Before I began this, I had dull skin, brittle hair and nails, headaches, distractibility, irritability, fatigue, sleep issues, pressure fluctuations, and arrhythmia. I take about 800 mg in two doses. Alongside the subtle, yet significant work magnesium does within my body, I cherish its ability to bring balance.
Read More
9
Eliminated arrhythmia
5 people found this helpful
I consistently take magnesium. My daughter recommended it for my health, which prompted me to start. Previously, I dealt with constipation, but I've been improving. I also had irregular heartbeats and needed medication. Since taking this, my arrhythmia has ceased, and I've discontinued the medicine. It's a superb supplement.
Read More
9
Calmed arrhythmia
I purchased this magnesium and took 2 tablets three times daily for several months. As a result, my arrhythmia has calmed, my nervousness lessened, and I've no longer experienced sudden blood pressure surges.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
- All Researches
9
We evaluated how magnesium, given intravenously, impacts the effectiveness of ibutilide in converting atrial flutter or fibrillation. In a group of 229 patients, we found that those who received magnesium alongside ibutilide had a significantly higher success rate in chemical conversion—78% more likely than those who did not receive magnesium. A dose of 4 grams seemed to provide the best results. Overall, magnesium appears to enhance the efficacy of ibutilide without major complications.
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9
We explored the effectiveness of ibutilide in converting atrial flutter or fibrillation after amiodarone treatment didn’t work. In this clinical study conducted in an ICU, we monitored 26 patients with persistent arrhythmias. After giving each patient ibutilide, along with magnesium for better results, we found that 81.5% converted to normal sinus rhythm.
However, while many responded well, 11% experienced some nonsustained heart rhythm complications. This indicates ibutilide can be a reliable option when amiodarone fails, with minimal serious side effects.
However, while many responded well, 11% experienced some nonsustained heart rhythm complications. This indicates ibutilide can be a reliable option when amiodarone fails, with minimal serious side effects.
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8
Magnesium enhances ibutilide's effectiveness
We explored the combination of magnesium and ibutilide to help convert persistent atrial flutter or fibrillation in patients with rheumatic heart disease. In this study with 33 patients, raising magnesium levels significantly improved the rate of conversion to normal sinus rhythm. Astonishingly, 76% of patients successfully transitioned to sinus rhythm post-treatment. The analysis indicated that higher magnesium levels, particularly above 3.8 mg/dl, were linked to increased success rates. This suggests that magnesium could enhance ibutilide’s effectiveness in treating these heart rhythm issues.
Read More
8
We examined the role of high doses of magnesium in enhancing the safety and effectiveness of ibutilide for converting atrial flutter to normal sinus rhythm.
A study involving 476 patients revealed that those who received magnesium alongside ibutilide had a higher conversion rate to normal rhythm and experienced significantly fewer ventricular complications.
With only 1.2% of magnesium patients developing serious issues compared to 7.4% in those who only got ibutilide, it’s clear that magnesium offers protective benefits.
A study involving 476 patients revealed that those who received magnesium alongside ibutilide had a higher conversion rate to normal rhythm and experienced significantly fewer ventricular complications.
With only 1.2% of magnesium patients developing serious issues compared to 7.4% in those who only got ibutilide, it’s clear that magnesium offers protective benefits.
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8
Magnesium enhances dofetilide effectiveness
We investigated whether intravenous magnesium enhances the effectiveness of dofetilide in converting atrial flutter (AFL) or fibrillation (AF) to normal sinus rhythm. The study included 160 patients who received dofetilide, with some also getting magnesium.
While the overall success rate of conversion was 41.9%, those treated with magnesium had a 107% increase in chances of successful cardioversion compared to those who did not receive it. This highlights that magnesium could indeed be beneficial when used alongside dofetilide in managing AF or AFL.
While the overall success rate of conversion was 41.9%, those treated with magnesium had a 107% increase in chances of successful cardioversion compared to those who did not receive it. This highlights that magnesium could indeed be beneficial when used alongside dofetilide in managing AF or AFL.
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User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Promotes calmness
41 people found this helpful
Calmness, balance, sleep - that's what I experience. I can't speak for others, but it aids me in managing overwork, calming my nerves. Before I began this, I had dull skin, brittle hair and nails, headaches, distractibility, irritability, fatigue, sleep issues, pressure fluctuations, and arrhythmia. I take about 800 mg in two doses. Alongside the subtle, yet significant work magnesium does within my body, I cherish its ability to bring balance.
Read More
9
Eliminated arrhythmia
5 people found this helpful
I consistently take magnesium. My daughter recommended it for my health, which prompted me to start. Previously, I dealt with constipation, but I've been improving. I also had irregular heartbeats and needed medication. Since taking this, my arrhythmia has ceased, and I've discontinued the medicine. It's a superb supplement.
Read More
9
Calmed arrhythmia
I purchased this magnesium and took 2 tablets three times daily for several months. As a result, my arrhythmia has calmed, my nervousness lessened, and I've no longer experienced sudden blood pressure surges.
Read More
9
Stops arrhythmia
Magnesium has beneficial effects, including normalising heart rate, lowering blood pressure, regulating blood sugar, eliminating muscle cramps, and reducing joint pain. When combined with calcium, it increases bone mineral density. Remarkably, my mother's arrhythmia resolved while using magnesium!
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9
Supports sleep improvement
Magnesium has aided me with insomnia, arrhythmia, and stress. After several years of use, it helps me fall asleep easily and wake refreshed. My stress levels are lower, and previously frequent arrhythmia events have decreased to once a month. I highly recommend it!
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Frequently Asked Questions
9
Calmed arrhythmia
I purchased this magnesium and took 2 tablets three times daily for several months. As a result, my arrhythmia has calmed, my nervousness lessened, and I've no longer experienced sudden blood pressure surges.
9
Supports sleep improvement
Magnesium has aided me with insomnia, arrhythmia, and stress. After several years of use, it helps me fall asleep easily and wake refreshed. My stress levels are lower, and previously frequent arrhythmia events have decreased to once a month. I highly recommend it!
7.5
Promotes calmness
41 people found this helpful
Calmness, balance, sleep - that's what I experience. I can't speak for others, but it aids me in managing overwork, calming my nerves. Before I began this, I had dull skin, brittle hair and nails, headaches, distractibility, irritability, fatigue, sleep issues, pressure fluctuations, and arrhythmia. I take about 800 mg in two doses. Alongside the subtle, yet significant work magnesium does within my body, I cherish its ability to bring balance.
9
Eliminated arrhythmia
5 people found this helpful
I consistently take magnesium. My daughter recommended it for my health, which prompted me to start. Previously, I dealt with constipation, but I've been improving. I also had irregular heartbeats and needed medication. Since taking this, my arrhythmia has ceased, and I've discontinued the medicine. It's a superb supplement.
7.5
Aids recovery post-birth
The benefits are clear. I take it for a month after every two. Following my second birth, I experienced arrhythmia; this helped. It's more cost-effective than pharmacy options and assists with insomnia, apathy, fatigue, and stress. I've tried it and recommend it.
9
Stops arrhythmia
Magnesium has beneficial effects, including normalising heart rate, lowering blood pressure, regulating blood sugar, eliminating muscle cramps, and reducing joint pain. When combined with calcium, it increases bone mineral density. Remarkably, my mother's arrhythmia resolved while using magnesium!
6
Reduced tremor
2 people found this helpful
My heart experienced arrhythmia, leading me to seek this out, suspecting a magnesium deficiency. I'm using other supplements too, yet I've noticed significant reduction in tremors. The dosage seems adequate, and I intend to continue using it.
7.5
Less arrhythmia attacks
1 people found this helpful
This has positively impacted my heart, noticeably reducing arrhythmia attacks. My sleep has also improved. I didn't give it 5 stars solely due to its laxative effect, which may be due to my personal characteristics.
References
- Kukendrarajah K, Ahmad M, Carrington M, Ioannou A, Taylor J, et al. External electrical and pharmacological cardioversion for atrial fibrillation, atrial flutter or atrial tachycardias: a network meta-analysis. Cochrane Database Syst Rev. 2024;6:CD013255. 10.1002/14651858.CD013255.pub2
- Malkoc A, Phan A, Falatoonzadeh P, Mac O, Sherman W, et al. Gender Differences With Ibutilide Effectiveness and Safety in Cardioversion of Atrial Fibrillation. J Surg Res. 2024;296:10. 10.1016/j.jss.2023.12.002
- Malviya A, Kapoor M, Sivam RKN, Khan SA, Pandey R, et al. Ibutilide with magnesium for conversion of atrial fibrillation or flutter in rheumatic heart disease patients: Ibutilide with magnesium for chemical cardioversion of atrial fibrillation or flutter. Indian Heart J. 2020;72:283. 10.1016/j.ihj.2020.07.008
- Wang A. Efficacy of class III antiarrhythmics and magnesium combination therapy for atrial fibrillation. Pharm Pract (Granada). 2012;10:65. PubMed
- Patsilinakos S, Christou A, Kafkas N, Nikolaou N, Antonatos D, et al. Effect of high doses of magnesium on converting ibutilide to a safe and more effective agent. Am J Cardiol. 2010;106:673. 10.1016/j.amjcard.2010.04.020
- Coleman CI, Sood N, Chawla D, Talati R, Ghatak A, et al. Intravenous magnesium sulfate enhances the ability of dofetilide to successfully cardiovert atrial fibrillation or flutter: results of the Dofetilide and Intravenous Magnesium Evaluation. Europace. 2009;11:892. 10.1093/europace/eup084
- Steinwender C, Hönig S, Kypta A, Kammler J, Schmitt B, et al. Pre-injection of magnesium sulfate enhances the efficacy of ibutilide for the conversion of typical but not of atypical persistent atrial flutter. Int J Cardiol. 2010;141:260. 10.1016/j.ijcard.2008.12.012
- Tercius AJ, Kluger J, Coleman CI, White CM. Intravenous magnesium sulfate enhances the ability of intravenous ibutilide to successfully convert atrial fibrillation or flutter. Pacing Clin Electrophysiol. 2007;30:1331. PubMed
- Bregvadze IN, Maĭkov EB, Bil'dinov OA, Kratskina TL, Klimenko IuL, et al. [The efficacy and safety of nibentan for pharmacological cardioversion in patients with persistent atrial fibrillation and flutter: the role of dose limitation and magnesium sulfate administration]. Kardiologiia. 2007;47:48. PubMed
- Sedrakyan A, Treasure T, Browne J, Krumholz H, Sharpin C, et al. Pharmacologic prophylaxis for postoperative atrial tachyarrhythmia in general thoracic surgery: evidence from randomized clinical trials. J Thorac Cardiovasc Surg. 2005;129:997. PubMed
- Kalus JS, Spencer AP, Tsikouris JP, Chung JO, Kenyon KW, et al. Impact of prophylactic i.v. magnesium on the efficacy of ibutilide for conversion of atrial fibrillation or flutter. Am J Health Syst Pharm. 2003;60:2308. PubMed
- Caron MF, Kluger J, Tsikouris JP, Ritvo A, Kalus JS, et al. Effects of intravenous magnesium sulfate on the QT interval in patients receiving ibutilide. Pharmacotherapy. 2003;23:296. PubMed
- Hennersdorf MG, Perings SM, Zühlke C, Heidland UE, Perings C, et al. Conversion of recent-onset atrial fibrillation or flutter with ibutilide after amiodarone has failed. Intensive Care Med. 2002;28:925. PubMed
- Jensen BM, Alstrup P, Klitgård NA. Magnesium substitution and postoperative arrhythmias in patients undergoing coronary artery bypass grafting. Scand Cardiovasc J. 1997;31:265. PubMed
- Joshi PP, Deshmukh PK, Salkar RG. Efficacy of intravenous magnesium sulphate in supraventricular tachyarrhythmias. J Assoc Physicians India. 1995;43:529. PubMed
- Casthely PA, Yoganathan T, Komer C, Kelly M. Magnesium and arrhythmias after coronary artery bypass surgery. J Cardiothorac Vasc Anesth. 1994;8:188. PubMed
